Cell Cocktail Rice-resistant cancer cells, Nice to normal cells

Juice rice cells can knock out two types of human cancer cells as well or better than the potent anticancer drug Taxol, a scientist at Michigan Technological University discovered in laboratory tests. Moreover, Taxol does something you can not do: playing well with normal cells.
Biologist Wusirika Ramakrishna and his team made their fight against cancer shaker with drops of rice stem cells called callus, grown in the lab using garden-variety seed plant rice Oryza sativa. Then secretions collected from these calli and applied to the cells of the colon and kidney cancer in laboratory.
After 96 hours exposure to a solution of 20-a callus of rice-1, 95 percent of kidney cancer cells were killed along with 83 percent of colon cancer cells, while normal cells lung were virtually unscathed. Taxol was lethal to cancer cells well, but also kill significant numbers of normal cells.
Wusirika believes the rice callus culture can attack the cancer with the same kind of plant chemicals that make very healthy vegetables to eat.
"They are full of metabolic compounds that are good for us," he says. "We believe that is what is killing the cancer."
Then test the solution Wusirika like rice callus in the prostate, lung and breast cancer cells, the most common types of cancer .. "We will work with all of them, but we have to find out," he said.
He also wants to determine which of the compounds released by the rice callus has cancer-fighting properties and how they work against tumor cells. Or, he says, it is possible that the suite of biochemicals in callus solution work as a team to fight cancer.

'Anchors' Organize chromosomal DNA during cell division

'Anchors' Organize chromosomal DNA during cell division: New role of telomeres in cell growth may shed light on aging and age-related diseases

For humans to grow and to replace and heal damaged tissue, the cells of the body must play continuously, a process known as "cell division", by which a cell becomes two, two become four, and so successively. A key question is how bio-medical research chromosomes that are duplicated during cell division so that each daughter cell receives an exact copy of the genome of a person, are organized during this process.
Now, scientists at the Salk Institute have discovered a new function of human cell division that can help explain how DNA is organized in the nucleus of cells reproduce. They found that telomeres, molecular caps protect the ends of chromosomes move toward the outer edge of the cell nucleus after they have been duplicated.
This image shows the telomeres (yellow), protective caps on the ends of chromosomes that have been moved to the outer edge of a cell nucleus (blue). Salk researchers discovered that anchor telomeres to the nuclear membrane after the cell duplicates its DNA during cell division, which can help organize chromosomes as the cell divides into two daughter cells.
While the consequences of this spatial reorganization of telomeres are not yet clear, the findings could shed light on how our genes are regulated and how programs are altered gene expression during cell division, an important step in understanding the aging and diseases arising from genetic mutations, such as cancer.
"What we have discovered is that telomeres not only protect our chromosomes, also help organize our genetic material in the nucleus," says Jan Karlseder, a professor in the Salk Laboratory of Molecular and Cellular Biology and Darlene Shiley President and Donald. "This is important, because the three-dimensional position of the DNA in the nucleus influences gene expression profiling and how it changes over time in the genome."
Telomeres, a combination of protein and DNA are vital in DNA replication aging and tumor suppression. Whenever a primary human cell divides, the telomeres shorten until critically short telomeres lead to cell destruction. Much research has been focused on understanding the dynamics Karlseder telomeres to develop ways to influence the aging process, and thus limit the growth of cancer cells.
Besides explore the involvement of telomeres in aging syndromes and interactions between the mechanism of DNA damage and telomere Karlseder studies the role of telomeres during cell cycle. Previous studies on human cells have shown that telomeres change position during cell division, suggesting that also may play a role in the organization of the DNA into nuclei. However, these studies only provide instant telomeres isolated at different stages of the cell cycle.
In their new study, the researchers used advanced time lapse confocal microscopy Salk live cells to track the movement of telomeres in real time during the cell cycle. Continued for 20 hours telomeres in living cells molecules by labeling with bright under a microscope. They also recorded the movement of chromatin, a combination of DNA and proteins that form chromosomes.

Breast cancer risk increases

Breast cancer risk increases with repeated CT Nuclear Estimates :

Researchers reviewed the records of about 250,000 women included in an integrated system to provide health services found that the increased use of CT between 2000 and 2010 could result in an increased risk of breast cancer in some women, even younger patients and receiving the repeated examinations. According to the study, which was presented today at the annual meeting of the Radiological Society of North America (RSNA), nuclear medicine examinations can also help increase breast cancer risk.CT ionizing radiation such as X-ray use produces cross-sectional images of the body. In nuclear medicine imaging, radio-pharmaceuticals - a compound that includes a small amount of a radioactive material - is given in the body to help visualize internal organs.

"When a woman undergoes CT or nuclear medicine imaging of the chest, abdomen or spine, breast tissue can absorb some of the radiation," said lead author Rebecca Smith-Bind-man, MD, professor of radiology and imaging Bio-medical at University of California, San Francisco. "Breast tissue is one of body tissues known to be susceptible to developing cancer as a result of exposure to radiation."

The study, led by Ginger Feliz, MD, MPH, fellow breast images Prentice Women's Hospital - Northwestern Memorial Hospital in Chicago, found that among the female members of the system, the use of CT increased by 99.8 TC 1,000 women in 2000 to 192.4 CT scans per 1,000 women in 2010 (an annual increase of 6.8 percent). In 2010, 46 percent of CT scans of the chest exposed to radiation. Nuclear medicine imaging lines declined from 39.3 per 1,000 women in 2000 to 27.5 lines per 1,000 women in 2010 (a decrease of 3.5 percent per year), however, in 2010, 84 percent of nuclear medicine studies exposed to radiation from the breast.

"So far, the impact of the increasing use of images in radiation exposure to breast tissue and subsequent risk of breast cancer is unknown," said Dr. Smith-Bindman. "Our goal was to quantify the use of imaging and radiation exposure to the breast among women who participated in delivery of integrated health system and use this data to determine the risk of images related to breast cancer in these studies. "

The research team collected information CT dose of 1,656 patients that underwent CT examinations exposed to radiation from the breast and, using a new method of automated calculation calculates the effective radiation dose patients and the amount of radiation absorbed in the chest. The team also analyzed the volume radio-pharmaceutical and associated radiation exposure to 5507 used in nuclear medicine procedures that exposed his chest to radiation. "We found that the estimated radiation dose for breast CT were highly variable between patients, with higher doses coming multipurpose cardiac CT and chest, where successive images are captured studied organ," said Dr. Smith-Bind-man.